Dinah Loerke, PhD

Dinah Loerke

Associate Professor

  • Faculty
  • College of Natural Sciences and Mathematics
  • Department of Physics and Astronomy

What I do

Associate Professor with a research and teaching focus on biophysics, biomechanics, imaging, and quantitative computational analysis and modeling

Specialization(s)

biophysics, imaging

Degree(s)

  • Ph.D., Biophysics, University of Goettingen, 2004
  • MS, Physics, University of Goettingen, 1998

Licensure / Accreditations

  • IRBNet Board SL-1 Lab Certification
  • Adult CPR/AED

Research

molecular and mechanical regulation of morphogenesis, regulation of clathrin-coated pit maturation

Key Projects

  • The Biomechanics of Intercalation in Germ-Bank Elongation
  • Deconstructing The Cell's Mechanical Circuits
  • Cottrell Scholar Award

Featured Publications

Jewett, C. E., Vanderleest, T. E., Miao, H., Xie, Y., Madhu, R., Loerke, D., & Blankenship, J. T. (2017). Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium. Nature Communications, 8.
Kadlecova , Z., Spielman, S. J., Loerke, D., Mohanakrishnan, A., Reed, D. K., & Schmid, S. L. (2017). Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2. Journal of Cell Biology.
Loerke, D., Mettlen, M., Yarar, D., Jaqaman, K., Jaqaman, H., Danuser, G., & Schmid, S. L. (2009). Cargo and dynamin regulate clathrin-coated pit maturation. PLoS biology, 7(3), e57.
Loerke, D., Mettlen, M., Schmid, S., & Danuser, G. (2011). Measuring the hierarchy of molecular events during clathrin-mediated endocytosis. Traffic, 12(7), 815-825.
Loerke, D., le Duc, Q., Blonk, I., Kerstens, A., Spanjaard, E., Machacek, M., et al. (2012). Quantitative Imaging of Epithelial Cell Scattering Identifies Specific Inhibitors of Cell Motility and Cell-Cell Dissociation. Science Signaling , 5(231).

Awards

  • 2017 Scialog Fellow, Research Corporation for Science Advancement